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Pharmacokinetic Data
Pharmacokinetic Data
DRUG Dose Interval Route Min Max Half-life
(mg/kg) (Hours) mcg/mL mcg/mL (hours)
-------------- -------- -------- ----- ---- ------ ---------
phenobarbital <8.8 q812h PO 20 40 53
phenytoin (dog) 35 q8h PO 10 20 3.3
phenytoin (cat) 10 --- PO 10 20 24
Digoxin (dog) 0.011 q12h PO 0.9 ng 3.0 ng 31
Digoxin (cat) 0.008 q12h PO 0.9 ng 2.0 ng 33
Gentamicin 2.2 q8h IM,SQ <1 <10 0.9-1.3
Amikacin 10-15 <=5 <30
Procainamide 4 10 2
Prices: Spring 95 --> current = $13.10 / sample internal
$19.80 / sample external
STANDARDS:
Phenobarbital:
L 13.5 to 16.5 mcg/mL
M 27.0 to 33.0 mcg/mL
H 45.0 to 55.0 mcg/mL
Phenytoin
L 6.75 to 8.25 mcg/mL
M 13.5 to 16.5 mcg/mL
H 27.0 to 33.0 mcg/mL
Gentamicin
L 0.85 - 1.15 mcg/mL
M 3.6 - 4.4 mcg/mL
H 7.2 - 8.8 mcg/mL
Digoxin
L 0.55 - 0.95 ng/mL
M 1.30 - 1.70 ng/mL
H 3.15 - 3.85 ng/mL
Gordon L. Coppoc, DVM, PhD
Email: coppoc@vet.purdue.edu
Last mdified (yymmdd) 950830
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Pharmacokinetic Data
Pharmacokinetic Data
DRUG Dose Interval Route Min Max Half-life
(mg/kg) (Hours) mcg/mL mcg/mL (hours)
-------------- -------- -------- ----- ---- ------ ---------
phenobarbital <8.8 q812h PO 20 40 53
phenytoin (dog) 35 q8h PO 10 20 3.3
phenytoin (cat) 10 --- PO 10 20 24
Digoxin (dog) 0.011 q12h PO 0.9 ng 3.0 ng 31
Digoxin (cat) 0.008 q12h PO 0.9 ng 2.0 ng 33
Gentamicin 2.2 q8h IM,SQ <1 <10 0.9-1.3
Amikacin 10-15 <=5 <30
Procainamide 4 10 2
Prices: Spring 95 --> current = $13.10 / sample internal
$19.80 / sample external
STANDARDS:
Phenobarbital:
L 13.5 to 16.5 mcg/mL
M 27.0 to 33.0 mcg/mL
H 45.0 to 55.0 mcg/mL
Phenytoin
L 6.75 to 8.25 mcg/mL
M 13.5 to 16.5 mcg/mL
H 27.0 to 33.0 mcg/mL
Gentamicin
L 0.85 - 1.15 mcg/mL
M 3.6 - 4.4 mcg/mL
H 7.2 - 8.8 mcg/mL
Digoxin
L 0.55 - 0.95 ng/mL
M 1.30 - 1.70 ng/mL
H 3.15 - 3.85 ng/mL
Gordon L. Coppoc, DVM, PhD
Email: coppoc@vet.purdue.edu
Last mdified (yymmdd) 950830
glc
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