SPIE Call for Papers and Announcement

Imaging, Manipulation and Analysis of Biomolecules,
Cells, and Tissues IV BO124


Part of SPIE’s International Symposium on Biomedical Optics (BiOS) 2007 20-25 January 2007 • San Jose Convention Center • San Jose, CA USA

Conference Chairs: Daniel L. Farkas, Cedars-Sinai Medical Ctr.; Robert C. Leif, Newport Instruments; Dan V. Nicolau, The Univ. of Liverpool (United Kingdom)

Conference Cochairs J. P. Robinson, Purdue Univ.; Attila Tarnok, Univ. Leipzig (Germany); Ramesh Raghavachari, U.S. Food and Drug Administration


Program Committee: Christopher H. Contag, Stanford Univ.; Paul Dan A. Cristea, Univ. Politehnica Bucharest (Romania); Alberto Diaspro, Univ. degli Studi di Genova (Italy); Erik G. Fällman, Umeå Univ. (Sweden); Jesper Gluckstad, Risø National Lab. (Denmark); Ewa M. Goldys, Macquarie Univ. (Australia); James F. Leary, Purdue Univ.; Charles P. Lin, Massachusetts General Hospital; Andreas Nowatzyk, Carnegie Mellon Univ.; Markus Sauer, Institut für Neue Materialien GmbH (Germany)

This interdisciplinary conference addresses the knowledge continuum from molecular structure and fundamental mechanisms to biological and medical applications, focusing on new approaches to imaging, manipulation, and analysis of biomolecules, cells and tissues, both in vitro and in vivo. The conference will report on the latest developments in functional and multispectral imaging, optical manipulation, analytical cytology (cytomics), cellular imaging algorithms and quantification. The principal aim is to further improve the interdisciplinary dialog between those who design and implement critical technologies and the primary users who study important problems that drive developments, in order to advance translational research.

Reports of original research contributions are solicited on the following topics:

Functional imaging of biomolecules, live cells and tissues:

·         light microscopy of living cells and tissues (2D, 3D, 4D)

·         spectral imaging of multiple cellular and tissue components

·         new and automated methods for monitoring biological structure and physiology

·         microscopic imaging of electric potentials and events

·         mesoscopic (microscopic resolution in vivo) tissue imaging

·         multimodality tissue imaging in vivo.

Optical techniques for regenerative medicine:

·         stem cell characterization in vitro

·         stem cell imaging and tracking in vivo

·         in vivo studies of immunologic events

·         imaging methods in organ transplantation

·         functional monitoring of tissue engineering constructs

·         imaging of tissue oxygenation and vascularization.

Functional imaging and optical manipulation of biomolecules, live cells and tissues:

·         cell micromanipulation using optical trapping

·         cellular effects of localized energy deposition into micro- and nano-absorbers

·         cells and biomolecules in micro and nanoconfined spaces

·         scanning probe microscopy of cells and surface-immobilized biomolecules

·         microarray methods for cells and tissues

Manipulation and microarrays

·         new technology

·         new applications

Advanced analytical cytology of fixed cells (cytomics):

·         new methods and technologies for multispectral and multiparameter imaging, including acquisition, segmentation and analysis methods

Fluorescence and phosphorescence lifetime imaging

·         probes, including new dyes

·         high throughput cytometry

Rare event detection

·         new methods for cell separation including high-speed, optical and magnetic-paramagnetic sorting

·         circulating stem, fetal, cancer, and other rare cells

·         digital imaging for quantitative pathology

·         new components for analytical cytology instrumentation, including ultraminiature and nano systems

Clinical & research applications of analytical cytology

·         new and unusual applications of analytical cytology.

Image processing, quantification, standards, and display methods:

·         cell-based high throughput and high content screening

·         clustering algorithms

·         analytical quantification, including new methods for multiparameter cell analysis and data manipulation

·         automated 3D image processing, including tracking of tissue section surfaces, image segmentation, and fluorometry/densitometry

·         software standards and regulatory requirements for spectroscopy, flow cytometry, and imaging

·         image formats, databasing and retrieval

·         advanced image registration and display methods, including co-display of multimodality image sets.



Abstract Due Date: 10 July 2006

Manuscripts Due Date: 2 January 2006

Please send technical questions to Robert C. Leif, email rleif@rleif.com

The call for papers is located at http://spie.org/Conferences/calls/07/pw/